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【校友风采】吴紫云:膳食营养、先天免疫与生物衰老研究领域专家

日期:2021.08.28 点击:

       吴紫云校友,海南大学2002级生物技术专业本科、2006级作物遗传育种专业硕士,2014年获新加坡国立大学食品科学与工程博士学位,2014年至2019年于哈佛大学医学院/Joslin糖尿病研究中心从事博士后研究。现任上海交通大学农业与生物学院长聘教轨副教授,博士生导师,独立课题组组长。

吴紫云校友长期从事食品营养与生物衰老相关研究,成果显著。2019年以第一作者在Cell Metabolism(IF=27)发表研究论文,引起了学术界知名学者的高度关注,该成果被哈佛医学院主页等多个媒体报道。以第一作者在Cell Metabolism和BMC Biology等期刊发表SCI论文多篇。先后荣获国际食品科技联盟青年科学家奖(2016年)、上海市浦江人才计划项目(2020年)和上海市海外高层次人才计划项目(2021年)资助。




近期代表论文:

1.Wu Z, Isik M, Moroz N, Steinbaugh MJ, Zhang P and Blackwell TK. Dietary restriction extends lifespan through metabolic regulation of innate immunity. Cell Metabolism, 2019, 29, 1192-1205. (Three F1000Prime Recommendations, Research Highlights by Nature Reviews Endocrinology & Molecular Cell)

2.Wu Z, Senchuk MM, Dues DJ, Johnson BK, Cooper JF, Lew L, Machiela E, Schaar CE, DeJonge H, Blackwell TK and Van Raamsdonk JM. Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways. BMC Biology, 2018, 16, 147.

3.Wu Z, Song L, Liu S and Huang D. Tanshinones extend chronological lifespan in budding yeast Saccharomyces cerevisiae. Applied microbiology and biotechnology, 2014, 98(20), 8617-8628.

4.Liu Y, Wu Z*, Feng S, Yang X, Huang D. Hormesis of glyceollin I, an induced phytoalexin from soybean, on budding yeast chronological lifespan extension. Molecules, 2014, 19(1), 568-580.

5.Wu Z, Liu S, and Huang D. Independent and additive effects of glutamic acid and methionine on yeast longevity. Plos One, 2013, 8(11): e79319.

6.Wu Z, Liu S and Huang D. Dietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiae. Plos One. 2013, 8(5): e64448. doi:10.1371/journal.pone.0064448.

7.Wu Z, Song L, Feng S, Liu Y, He G, Yioe Y, Liu S and Huang D. Germination dramatically increases isoflavonoid content and diversity in chickpea (Cicer arietinum L.) seeds. Journal of Agricultural and Food Chemistry. 2012, 60, 8606−8615.

8.Wu Z, Song L, Liu S and Huang D. A high throughput screening assay for determination of chronological lifespan of yeast. Experimental Gerontology. 2011, 46, 915-922.

9.Wu Z, Song L and Huang D. Food grade fungal stress on germinating peanut seeds induced phytoalexins and enhanced polyphenolic antipxidants. Journal of Agricultural and Food Chemistry. 2011, 59, 5993−6003.